SANTA MONICA, Calif., April 25, 2017 /PRNewswire/ — The American College of Cardiology and the American Heart Association («ACC/AHA») published guidelines on lower extremity peripheral artery disease and syncope, along with the supporting systematic review on syncope. These jointly developed guidelines were simultaneously published in both Circulation and the Journal of the American College of Cardiology (JACC). Doctor Evidence, a software and services technology company that finds, categorizes and synthesizes data from published sources, assisted in the process.

Pacing as a Treatment for Reflex-Mediated (Vasovagal, Situational, or Carotid Sinus Hypersensitivity) Syncope: A Systematic Review for the 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope was published in both JACC and Circulation. Paul D. Varosy, MD, FACC, FAHA, FHRS chaired the joint Evidence Review Committee which worked closely with Doctor Evidence teams for the comprehensive and systematic search and rigorous analyses. In addition to the innovative technology platforms, Doctor Evidence provided methodology, library, data integrity, ontology management, and other services to support the performance of this evidence review.

The accompanying guideline, the 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope, chaired by Win-Kuang Shen, MD, FACC, FAHA, FHRS and a writing committee of 15 others, along with the joint guideline taskforce of 17 other distinguished cardiology researchers, was also published in both JACC and Circulation. The authors based the clinical recommendations on the results of the systematic review.

«We are proud to be the evidence partner for the American College of Cardiology and American Heart Association guideline development teams to bring evidence-informed recommendations to patients and cardiologists,» stated Robert Battista, CEO and co-founder of Doctor Evidence. «The mission of Doctor Evidence’s GROWTH initiative is to spread evidence-based medicine and methods widely and deeply, which is facilitated through the excellent collaborations we have with these well-respected guideline developers, along with many other medical professional societies, academic medical centers, and healthcare provider organizations.»

The 2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines was jointly published in JACC and Circulation in November 2016, with corrections appearing March 21, 2017. There was no need for independently produced systematic review because existing reviews met the criteria for the Evidence Review Committee. Doctor Evidence assisted with the identification and appraisal of the existing reviews.

The ACC and AHA have been members of GROWTH (Guidelines & Research Organizations Worldwide for Transparency & Harmonization) since 2014, when they selected GROWTH, a Doctor Evidence initiative, to assist in their guideline modernization efforts, to be compliant with the 2011 standards as set forth by the Institute of Medicine reports on trustworthy guidelines and systematic reviews. Both organizations have utilized the expertise and resources of Doctor Evidence for other evidence-based guideline projects during this time, including several that are still in development.

About Doctor Evidence and GROWTH
Doctor Evidence, LLC, founded in 2004 and headquartered in Santa Monica, CA, is a leader in technological solutions for Evidence-Based Medicine with a mission to provide stakeholders across the healthcare ecosystem with the most timely and relevant medical evidence and related analytics to make and inform the best clinical decisions. The Guideline & Research Organizations Worldwide for Transparency & Harmonization (GROWTH) initiative is committed to improving the health and quality of life of patients by encouraging the development of evidence‑based clinical recommendations through collaboration and resource‑sharing across the spectrum of evidence‑based medicine. GROWTH utilizes Doctor Evidence’s cutting‑edge platform technologies and services to synthesize high quality data from a broad variety of sources including databases of published clinical studies (e.g., PubMed or EMBASE), clinical, clinical practice guidelines, health technology assessments, systematic reviews, and epidemiological data. The resulting knowledge sets are leveraged, utilizing rigorous and transparent methodologies employing sophisticated analytic capabilities, to perform direct meta‑analyses, network meta‑analyses, meta‑regressions, cohort analyses, and sensitivity analyses. These reliable results then support transparent and trusted reviews informing clinical trial designs, guidelines and protocols for patient care, healthcare policy decisions, and ongoing research to identify the most efficacious and safe interventions for specific patients and populations.

For more information on the company and its products and services, please visit Visit to learn about GROWTH.


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SOURCE Doctor Evidence